abstract：:This year-long study investigated the epidemiology of acute filarial episodes due to Wuchereria bancrofti in 2 rural villages in south India. The annual incidence of 96.5 episodes/1000 population was significantly higher in males (108.5) than females (84.1) an strongly age dependent. First occurrence of acute disease ...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Ramaiah KD,Ramu K,Kumar KN,Guyatt H

更新日期：1996-11-01 00:00:00

abstract：:Peripheral blood mononuclear cells (PBMC) of patients with Indian visceral leishmaniasis (VL) suppressed the natural killer cell (NK) activity of normal human PBMC in vitro in a dose-dependent manner. Adherent monocytes, but not the non-adherent lymphocytes of VL patients suppressed NK activity through soluble mediato...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Chakrabarti G,Basu A,Manna PP,Bhattacharya S,Sen S,Bandyopadhyay S

更新日期：1996-09-01 00:00:00

abstract：:A modified nested polymerase chain reaction (PCR) method for detection of Plasmodium falciparum, P. vivax and P. malariae was combined with a simple blood collection and deoxyribonucleic acid (DNA) extraction method and evaluated in Malaysia. Finger-prick blood samples from 46 hospital patients and 120 individuals liv...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Singh B,Cox-Singh J,Miller AO,Abdullah MS,Snounou G,Rahman HA

更新日期：1996-09-01 00:00:00

abstract：:A dynamic model of the transmission of hepatitis B virus (HBV) was used to investigate some of the possible implications of the loss of vaccine-induced immunity on the effectiveness of mass HBV vaccination in high endemicity countries. The model, which describes the processes of horizontal and vertical transmission of...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Edmunds WJ,Medley GF,Nokes DJ

更新日期：1996-07-01 00:00:00

abstract：:In February 1995 we surveyed to chloroquine among patients with Plasmodium vivax malaria at Nias Island, in the Indian Ocean near north-western Sumatra, Indonesa. The subjects, 21 indigenous males and females (6-50 years old) infected with > 40 asexual blood stage parasites of P. vivax per microliter of blood, had mil...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Baird JK,Sustriayu Nalim MF,Basri H,Masbar S,Leksana B,Tjitra E,Dewi RM,Khairani M,Wignall FS

更新日期：1996-07-01 00:00:00

abstract：:Epidemics of cholera have been frequent in southern Africa since the reintroduction of the disease to the continent in 1970. In late 1992, following a severe drought and an influx of refugees from Mozambique, cholera reappeared in Zimbabwe for the first time since 1985 and rapidly spread through the rural areas of the...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Bradley M,Shakespeare R,Ruwende A,Woolhouse ME,Mason E,Munatsi A

更新日期：1996-07-01 00:00:00

abstract：:Routine results of direct examination of sputum smears for acid-fast bacilli from 34 laboratories in Tanzania were analysed. These represented 8 regions providing 94 laboratory-years of work; 61,580 tuberculosis suspects were evaluated with the aid of 141,371 smears. The average proportion of cases found among suspect...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Ipuge YA,Rieder HL,Enarson DA

更新日期：1996-05-01 00:00:00

abstract：:During April-October 1992 in Zambia, 1861 pregnant women attending prenatal clinics in 3 urban health centers in Lusaka and 5 district hospitals in various provinces were recruited to examine the association between HIV infection and hepatitis B virus (HBV) infection. 340 (18.3%) tested positive for HIV infection. H...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Oshitani H,Kasolo FC,Mpabalwani M,Mizuta K,Luo NP,Suzuki H,Numazaki Y

更新日期：1996-05-01 00:00:00

abstract：:In a previous study performed in south Sulawesi (Sulawesi Selatan), Indonesia, we established that the immunoglobulin G4 (IgG4) enzyme-linked immunosorbent assay (ELISA) is a suitable community diagnostic method and that it can distinguish areas of high and low prevalences within short distances. In an attempt to make...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Terhell AJ,Haarbrink M,Abadi K,Bronneberg DC,Tieleman MC,Asri M,Yazdanbakhsh M

更新日期：1996-03-01 00:00:00

abstract：:Urinary N-acetyl-beta-D-glucosaminidase (NAG; beta-N-acetylglucosaminidase; EC 3.2.1.30), blood urea, serum creatinine and creatinine clearance were measured in 23 patients bitten by Russell's viper (Daboia russelii siamensis), with systemic envenomation, at different time intervals after the bite during clinical obse...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Win-Aung,Aye-Kyaw,Tin-Win,San-Kun,Thin-Thin-Hlaing

更新日期：1996-03-01 00:00:00

abstract：:The sensitivities for Chagas disease diagnosis of haemoculture, xenodiagnosis, and polymerase chain reaction (PCR) amplification of Trypanosoma cruzi kinetoplast deoxyribonucleic acid (DNA) were compared for 101 patients living in an endemic region who were serologically positive for T. cruzi. PCR gave 60 positive res...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Junqueira AC,Chiari E,Wincker P

更新日期：1996-03-01 00:00:00

abstract：:This paper describes a large scale control programme for falciparum malaria in Xinyang prefecture, China, from the early 1980s to 1992. Falciparum malaria, transmitted mainly by Anopheles anthropophagus, was epidemic in Gusi, Huangchuan, Shangcheng and Huaibin counties in the prefecture in the early 1980s, 2922 cases ...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Dapeng L,Leyuan S,Xili L,Xiance Y

更新日期：1996-03-01 00:00:00

abstract：:The impact of concomitant human immunodeficiency virus (HIV) infection on the antibody response of onchocerciasis patients to Onchocerca volvulus antigens (OvAg) was studied by Western blotting and enzyme linked immunosorbent assay (ELISA). Immunoglobulin G (IgG) antibodies in sera from 45 HIV-sero-positive O. volvulu...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Tawill SA,Gallin M,Erttmann KD,Kipp W,Bamuhiiga J,Büttner DW

更新日期：1996-01-01 00:00:00

abstract：:When cross-sectional surveys are used to evaluate malaria intervention programmes in the community, the prevalence of morbidity is difficult to assess because of the fluctuating nature of malarial fever. We have therefore investigated the impact of bed net usage on 2 surrogate markers of malarial morbidity: (i) elevat...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： McGuire W,D'Alessandro U,Olaleye BO,Thomson MC,Langerock P,Greenwood BM,Kwiatkowski D

更新日期：1996-01-01 00:00:00

abstract：:In Ghana, a population-based immunization coverage survey revealed missed opportunities at preventive and curative care visits among children 12-18 months old attending the local hospital in the eastern region of Ghana. Parent-held immunization cards do not have a place to record curative care visits. If pediatric p...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Brugha R

更新日期：1995-11-01 00:00:00

abstract：:The factors which identify patients at risk of treatment failure were characterized in 1590 children and adults with uncomplicated falciparum malaria treated with 15 or 25 mg/kg of mefloquine on the borders of Thailand. Six independent predictors of failure were identified using multiple logistic regression. Age < or ...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： ter Kuile FO,Luxemburger C,Nosten F,Thwai KL,Chongsuphajaisiddhi T,White NJ

更新日期：1995-11-01 00:00:00

abstract：:Infantile visceral leishmaniasis (VL) was first reported from north Pakistan over 3 decades age in the remote valleys of the western Himalayas. These foci were reported as being completely devoid of domestic dogs. The later emergence of sporadic cases of infantile VL in the sub-Himalayan region of the country, where d...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Rab MA,Frame IA,Evans DA

更新日期：1995-11-01 00:00:00

abstract：:The polymerase chain reaction was applied to capillary blood spots dried on filter paper from 20 parasitologically proved cases of visceral leishmaniasis (VL), 21 subclinical cases, and 11 healthy controls in a longitudinal study of anthroponotic VL in Baringo District, Kenya. Leishmania deoxyribonucleic acid (DNA) wa...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Schaefer KU,Schoone GJ,Gachihi GS,Muller AS,Kager PA,Meredith SE

更新日期：1995-09-01 00:00:00

abstract：:In order to estimate the importance as a public health problem of skin diseases, we investigated the prevalence and severity of skin diseases in a representative sample of children in Mali. 1817 children were randomly selected in 30 clusters by probability-proportional-to-size sampling in Koulikoro region. The mean pr...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Mahé A,Prual A,Konaté M,Bobin P

更新日期：1995-09-01 00:00:00

abstract：:A limited outbreak of symptomatic intestinal and extraintestinal amoebiasis within a family complex is described. The infection was almost certainly transmitted by a Philippino housemaid, who was an asymptomatic carrier of Entamoeba histolytica infection acquired in her native country. Starch-gel electrophoresis showe...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Gatti S,Cevini C,Bruno A,Novati S,Scaglia M

更新日期：1995-07-01 00:00:00

abstract：:In order to understand better the relationship among Mycobacterium leprae, its transmission and the human host or the chain of infection which may lead to the development of leprosy, we performed a population survey in which nasal carriage of M. leprae was determined by a specific polymerase chain reaction (PCR), 2 ye...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Hatta M,van Beers SM,Madjid B,Djumadi A,de Wit MY,Klatser PR

更新日期：1995-07-01 00:00:00

abstract：:To determine the number of clients attending for voluntary human immunodeficiency virus (HIV) testing who are able to enter a trial of preventive therapy for tuberculosis, and the factors that determine who receives therapy, we studied 475 consecutive people attending for an HIV test at Lusaka's first voluntary HIV te...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Godfrey-Faussett P,Baggaley R,Mwinga A,Hosp M,Porter J,Luo N,Kelly M,Msiska R,McAdam K

更新日期：1995-07-01 00:00:00

abstract：:A prospective series of 156 patients systemically envenomed following the bite of a Papuan taipan (Oxyuranus scutellatus canni) were studied. All patients were treated with appropriate antivenom and clinical course and outcome were compared. The proportion of patients requiring intubation was significantly smaller, an...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Trevett AJ,Lalloo DG,Nwokolo NC,Naraqi S,Kevau IH,Theakston RD,Warrell DA

更新日期：1995-05-01 00:00:00

abstract：:Plasmodium falciparum in Thailand is highly resistant to available antimalarial drugs. Artemether, a derivative of artemisinin, is a promising compound currently used to cope with this situation but the course of treatment has to be at least 5 d. An effective short treatment course of this drug is possible when used i...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Karbwang J,Na-Bangchang K,Thanavibul A,Ditta-in M,Harinasuta T

更新日期：1995-05-01 00:00:00

abstract：:Leishmania lainsoni has recently been recognized as a new peripylarian species belonging to the subgenus Viannia and the L. braziliensis complex. It has been isolated from its sandfly vector, reservoir host and cutaneous lesions of human patients. Microscopical examination has shown characteristics which are different...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Eresh S,de Bruijn MH,Mendoza-León JA,Barker DC

更新日期：1995-03-01 00:00:00

abstract：:This communication reports 7 Ethiopian visceral leishmaniasis (VL) patients co-infected with human immunodeficiency virus (HIV). The clinical and laboratory findings in 6 patients did not differ from classical VL. All patients had highly elevated anti-leishmanial antibody titres, determined by immunoglobulin G-based e...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Berhe N,Hailu A,Wolday D,Negesse Y,Cenini P,Frommel D

更新日期：1995-03-01 00:00:00

abstract：:Between 1986 and 1993 visceral leishmaniasis (VL) was diagnosed in 50 adult patients with human immunodeficiency virus type 1 (HIV-1) infection (8 females, 42 males: 31 intravenous drug users, 11 homosexual or bisexual men, 6 heterosexual individuals, 2 blood recipients) from 5 hospital centres in southern France. Dia...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Rosenthal E,Marty P,Poizot-Martin I,Reynes J,Pratlong F,Lafeuillade A,Jaubert D,Boulat O,Dereure J,Gambarelli F

更新日期：1995-03-01 00:00:00

abstract：:The response in vitro of Plasmodium falciparum to chloroquine, mefloquine and quinine was studied in a hyperendemic peri-urban area of Accra, Ghana, during the fourth quarter of 1991, yielding a total of 159 valid tests. Schizont maturation in drug-free controls and effective chloroquine concentrations were strongly c...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Wernsdorfer WH,Landgraf B,Wiedermann G,Kollaritsch H

更新日期：1995-01-01 00:00:00

abstract：:Glucose-6-phosphate dehydrogenase (G-6-PD) deficiency surveys in Afghan refugees and a local community in the North-West Frontier Province, Pakistan, showed that this trait was most common among Pathan and Uzbak refugees (15.8% and 9.1% respectively). The prevalence among Pakistani Pathans was 7.0%, and that in Tajik ...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Bouma MJ,Goris M,Akhtar T,Khan N,Khan N,Kita E

更新日期：1995-01-01 00:00:00

abstract：:Visceral leishmaniasis (VL) was first reported in Pakistan over 30 years ago from the remote north-eastern Himalayan region. Sporadic cases are now widely reported from the Northern Areas, part of North-West Frontier Province (NWFP) and Punjab Province, together with Azad Jammu and Kashmir (AJK). Two hundred and thirt...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Rab MA,Evans DA

更新日期：1995-01-01 00:00:00

abstract：:The activity of bacitracin in vitro against Giardia intestinalis, Trichomonas vaginalis and Tritrichomonas foetus was enhanced 5-10 times by equimolar concentrations of zinc. Bacitracin and bacitracin zinc activity was tolerant to either aerobic or anaerobic culture conditions and equally effective against T. vaginali...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Andrews BJ,Mylvaganam H,Yule A

更新日期：1994-11-01 00:00:00

abstract：:The harmful effects of malaria are most pronounced during first pregnancies and chemoprophylaxis is most effective when given at this time. However, restriction of chemoprophylaxis to first pregnancies might lead to enhanced susceptibility to malaria during second pregnancies. We have investigated this possibility by ...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Greenwood AM,Menendez C,Alonso PL,Jaffar S,Langerock P,Lulat S,Todd J,M'Boge B,Francis N,Greenwood BM

更新日期：1994-11-01 00:00:00

abstract：:A community-based intervention trial was carried out to evaluate the effectiveness of alphamethrin-impregnated bed nets for control of Plasmodium vivax malaria and its vector in an area of moderate endemicity in southern Henan province, central China in 1990. Malaria incidence was significantly lower in the interventi...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Luo D,Lu D,Yao R,Li P,Huo X,Li A,Wen L,Ge C,Zhang S,Huo H

更新日期：1994-11-01 00:00:00

abstract：:An evaluation of the performance of the Kersey Nutrition Rehabilitation Centre in Nigeria was undertaken with particular focus on mortality, rate of weight gain, and the management strategy. During 1987-1991 the total number of admissions for protein-energy malnutrition (PEM) was 803. The age group most commonly repre...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Ibekwe VE,Ashworth A

更新日期：1994-09-01 00:00:00

abstract：:A population-based study of the clinical, laboratory and ultrasonographic findings in patients suffering from mild or moderate opisthorchiasis in Prachinburi province, Thailand was conducted in 1990-1992. The effectiveness of treatment with praziquantel at 40 mg/kg body weight was evaluated. After treatment, a long-la...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Pungpak S,Chalermrut K,Harinasuta T,Viravan C,Schelp PF,Hempfling A,Schlattmann P,Bunnag D

更新日期：1994-09-01 00:00:00

abstract：:This paper reports the morphological and biochemical characterization of the species of Schistosoma infecting humans in the Republic of São Tomé and Principe. The eggs are typical in shape and size of S. intercalatum, measuring on average between 174.5 microns and 189.1 microns. The eggs are voided in the faeces and n...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Southgate VR,Rollinson D,Kaukas A,Almeda J,Sousa AM,Castro F,Soares E,Corachan M

更新日期：1994-07-01 00:00:00

abstract：:Measured fever often forms the basis for defining clinical malaria episodes in children from endemic areas. We measured body temperature every 3 h from 08:00 to 20:00 in 69 children aged 1-5 years during the malaria season in a rural area of The Gambia. Body temperature varied on average by more than one degree Celsiu...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Schellenberg JR,Greenwood BM,Gomez P,Menendez C,Alonso PL

更新日期：1994-07-01 00:00:00

abstract：:The market for antimalarial drugs consists of the 2.8 billion (2.8 x 10(9) people living in malaria endemic areas and about 20-30 million people, mainly Europeans and North Americans, who travel or live in malarious areas, and the wealthy elite of malarious developing countries. Some of the largest markets include Chi...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Foster S

更新日期：1994-06-01 00:00:00

abstract：:The compounds derived from the Chinese medicinal plant qinghao (Artemisia annua) are the most rapidly acting of all antimalarial drugs. They are effective when given parenterally, orally or by suppository. No serious adverse effect has yet been reported in humans. The artemisinin derivatives already have an establishe...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： White NJ

更新日期：1994-06-01 00:00:00

abstract：:A sensitive high-performance liquid chromatographic method has been developed for the separation and quantitative estimation of melaminophenyl arsenical drugs used in the treatment of human and veterinary trypanosomiases. Five clinically relevant compounds (melarsoprol, melarsonyl potassium, cymelarsan, melarsen oxide...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Berger BJ,Fairlamb AH

更新日期：1994-05-01 00:00:00